Beckman Coulter Life Sciences has received 510(k) clearance from the FDA for the in vitro diagnostic use of its Navios flow cytometry system. The flow cytometer is intended for immunophenotyping in conjunction with proprietary Navios tetra software and CYTO-STAT tetraCHROME reagents. The system incorporates twelve detectors—ten fluorescence detectors and two light scattering detectors. Simultaneous measurements of integral, peak, and width are available for all scatter measurements and up to 10 fluorescent parameters. Ready to use, pre-optimized CYTO-STAT tetraCHROME reagents make sample preparation easy and a no-wash protocol reduces sample handling and increases laboratory safety. The Navios tetra system, for simultaneous identification and enumeration of T, B, and NK lymphocytes in whole blood, provides an easy-to-use solution for multicolor flow cytometric analysis of lymphocyte subsets as well as CD4+ and CD8+ T cell subset ratios.