The MVE Variō Series freezer offers an energy-efficient alternative for ultra-low temperature cryogenic storage. The dry sample storage area maintains a user-defined temperature between -20°C and -150°C while reducing the possibility of sample contamination by eliminating contact with liquid nitrogen, providing the safety margin and consistent temperature profile associated with LN2-based cryogenic storage. Additionally, the Variō freezer may be converted to a standard -196°C LN2.