HORIBA has expanded its compact hematology instrument range with the launch of new models with erythrocyte sedimentation rate (ESR) on board. The new Yumizen H550E (autoloader), H500E CT (closed tube), and Yumizen H500E OT (open tube) offer combined testing for CBC/DIFF with ESR results from whole blood in 60 seconds, adding an augmented profile for inflammatory disease assessment to the instruments’ functionality. HORIBA has developed the CoRA (Correlated Rouleaux Analysis) technology to integrate ESR into the new analyzers. Combining complete blood count (CBC) and 5-population white blood cell differential with rapid ESR (calibrated to the Westergren reference method) on one compact analyzer can help reduce cost per test as well as turnaround times. The Yumizen H550E and H500E models offer new connectivity for data management through HORIBA’s Yumizen P8000 middleware, along with Yumicare. This remote technical support tool helps secure the instrument connection to monitor workload, reagent consumption, quality control, and alarms.