Shimadzu announces the LCMS RX series of its triple quadruple mass spectrometry instruments. Supported by integrated hardware and software technologies, the systems come with a suite of innovative technologies, including CoreSpray, which enhances reliability by increasing gas flow and improving nebulizer coaxiality. The IonFocus electrode (now a standard feature across all RX models) helps remove matrix contaminants, resulting in lower noise levels, increased data quality, and reduced maintenance needs. The LCMS RX instruments enable efficient performance under challenging conditions. Enhanced software capabilities autonomously monitor the system, reducing the need for manual intervention, and the Performance Concierge proactively evaluates system performance, troubleshoots problems, and notifies operators of maintenance needs.